The National Institute of Neurological Disorders and Stroke (NINDS)
NINDS is the funding agency for the NIH StrokeNet Network. NINDS program staff are involved in the development of new StrokeNet proposals, as well as the management of funded proposals. StrokeNet Program Scientists provide scientific/administrative input.
NINDS StrokeNet Program Director: Scott Janis, PhD NINDS StrokeNet Program Official: Mariam M. Afzal, BA
NINDS StrokeNet Program Official: Sean McCarthy
The NIH StrokeNet National Coordinating Center (NCC)
The NCC is the operational hub that helps lead, organize, and oversee all StrokeNet clinical trials from early concept through final publication. It helps design and implement multi center stroke prevention, treatment, and recovery studies; coordinates steering committees, working groups, advisory groups, and community/patient input; and ensures the highest standards for patients, enrollment, and high quality trial conduct. The NCC manages regulatory approvals, IRB and DSMB communications, clinical trial agreements, site payments, study drug logistics, and central imaging in close partnership with the National Data Management Center (NDMC). It also leads education and career development for fellows and clinical research professionals and guides investigators through planning, implementation, analysis, and dissemination of trial results.
NCC Multiple Principal Investigators: Joseph P Broderick, MD & Pooja Khatri, MD
NCC Associate Director: Eva A. Mistry, MBBS, MSCI
The NIH StrokeNet National Data Management Center (NDMC)
The NDMC is the data and analytics backbone for all StrokeNet trials, designing and maintaining secure, web-based databases; developing case report forms, randomization, and data quality/monitoring plans; and ensuring high-quality, harmonized data collection across studies. It oversees data integrity, security, and sharing—from real-time reporting to DSMBs, FDA, and NINDS through to preparation of de-identified datasets for public repositories. The NDMC also provides expert statistical design and analysis support, including innovative/adaptive methods, and works closely with the NCC, RCCs, and project teams to support communication, trial status reporting, and recruitment/outreach platforms.
NDMC Multiple Principal Investigators: Jordan Elm, PhD, Wenle Zhao, PhD, & Catherine Dillon, MS