GET INVOLVED:

1. Strokenet Concept Synopsis v5 Updated January 2025
2. Process for Solicitation and Review of Clinical Trials  Updated May 2023
3. StrokeNet Working Groups
4. Grant Proposal Guidance for Investigators  Updated March 13, 2025

Funding Announcements:

1. Communicating and Acknowledging Federal Funding
2. NIH StrokeNet – National Data Management Center for year 2023 (U01 Clinical Trials Not Allowed) December 15, 2022
3. NIH StrokeNet – National Coordinating Center for year 2023 (U01 Clinical Trials Not Allowed) December 15, 2022
4. NIH StrokeNet- Regional Coordinating Stroke Centers for year 2023 (U24 - Clinical Trials Not Allowed) December 15, 2022
5. PAR-25-052 NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)  March 2025
   
6. Other Support
7. Biosketch Format Pages, Instructions and Samples
8. NOT-NS-14-043: Notice of Clarification of NINDS Policy for the Submission of Multi-site Clinical Trials in Stroke Treatment, Recovery, or Prevention

Administrative Documents:

1. Standard Operating Procedures (SOP's), Administrative and Good Clinical Practice 
2. Site Start-Up Timeline Expectations
3. Trial Payment Schedules and SOW
4. Guidance for Managing Competing Trials
5. Communication Escalation Process

Central IRB:

1. Institution-vs-IRB-responsibilities
2. StrokeNet Memo for Relying Institution Local IRB Processes

Network Publications:

1. #3488 Steiner ICH guideline ESJ 2025
2. Effect of sodium–glucose co-transporter-2 inhibitors on survival free of organ support in patients hospitalised for COVID-19 (ACTIV-4a): a pragmatic, multicentre, open-label, randomised, controlled, platform trial
3. Effect of the P-Selectin Inhibitor Crizanlizumab on Survival Free of Organ Support in Patients Hospitalized for COVID-19: A Randomized Controlled Trial
4. CREST‐2 Commitment to Rigorous Assessment of Carotid Stenting for Primary Prevention of Stroke
5. Apixaban vs Aspirin in Patients With Cancer and Cryptogenic Stroke A Post Hoc Analysis of the ARCADIA Randomized Clinical Trial
6. Adjunctive Intravenous Argatroban or Eptifibatide for Ischemic Stroke
7. Parent Council for a Pediatric Stroke Rehabilitation Clinical Trial
8. William M. Feinberg Lecture: Asymptomatic Carotid Stenosis: Current and Future Considerations
9. Tips for a Successful Scientific Presentation
10. Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy The ARCADIA Randomized Clinical Trial
11. National Institutes of Health StrokeNet During the Time of COVID-19 and Beyond
12. Recruitment in Acute Stroke Trials: Challenges and Potential Solutions
13. Multiomic markers stroke Nat Rev Neurol 2020
14. AF-SCREEN white paper post-stroke AF monitoring Circulation 2019
15. Atrial myopathy review JACC Basic to Translational 2019
16. Carotid revascularization and medical management for asymptomatic carotid stenosis - Hemodynamics (CREST-H): Study Design and rationale.
17. A pragmatic, adaptive clinical trial design for a rare disease: The FOcal Cerebral Arteriopathy Steroid (FOCAS) trial
18. The Utility of Domain-Specific End Points in Acute Stroke Trial
19. Stroke Recovery and Rehabilitation Research: Issues, Opportunities, and the National Institutes of Health StrokeNet
20. Imaging in StrokeNet: Realizing the Potential of Big Data
21. Intense Arm Rehabilitation Therapy Improves the Modified Rankin Scale Score: Association Between Gains in Impairment and Function
22. Efficacy of Home-Based Telerehabilitation vs In-Clinic Therapy for Adults After Stroke A Randomized Clinical Trial 
23. National Institutes of Health StrokeNet During the Time of COVID-19 and Beyond
24. Obstructive Sleep Apnea in Adults
25. Recommendations for Clinical Trials in ICH: The Second Hemorrhagic Stroke Academia Industry Roundtable.
26. Sleep for Stroke Management and Recovery Trial (Sleep SMART): Rationale and methods
27. National Institute of Health StrokeNet Training Core
28. The AtRial cardiopathy and antithrombotic drugs in prevention after cryptogenic stroke randomized trial: Rationale and methods.
29. Efficacy of home-based telerehabilitation vs in-clinic therapy for adults after stroke: A randomized clinical trial.
30. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging 
31. Study-aims-to-learn-more-about-silent-infarction-cognitive-decline-linked-to-silent-stroke
32. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. 
33. Stroke Recovery and Rehabilitation Research Issues, Opportunities, and the National Institutes of  Health StrokeNet. 
34. StrokeNet Takes Off National Institute of Neurological Disorders and Stroke Organizational Update. 
35. The NIH StrokeNet A Users Guide.
36. Imaging in StrokeNet Realizing the Potential of Big Data.
    

Research Practice Publications:

1. Electronic consent demonstrates potential to overcome “key barrier” in stroke trial recruitment  May 31, 2025 - Christopher Streib, Iris Davis
2. How Nurses Can Partner With National Institutes of Health StrokeNet to Deliver Best Research and Care to Stroke Patients. Stroke. 2017;STROKEAHA.117.017872 . Originally published December 4, 2017. Jamey Frasure, Judith Spilker
3. Power of an Adaptive Trial Design for Endovascular Stroke Studies: Simulations Using IMS (Interventional Management of Stroke) III Data. Stroke. 2016;47:2931-2937. Originally published November 15, 2016
   Maarten G. Lansberg, Ninad S. Bhat, Sharon D. Yeatts, Yuko Y. Palesch, Joseph P. Broderick, Gregory W. Albers, Tze L. Lai and Philip W. Lavori
4. Stroke Treatment Academic Industry Roundtable: The Next Generation of Endovascular Trials. Stroke. 2016;47:2656-2665. Originally published September 1, 2016
   Tudor G. Jovin, Gregory W. Albers, David S. Liebeskind and for the STAIR IX Consortium
5. Stroke Treatment Academic Industry Roundtable Recommendations for Individual Data Pooling Analyses in Stroke. 2016;47:2154-2159. Originally published July 12, 2016
   Kennedy R. Lees, Pooja Khatri, for the STAIR IX Collaborators